ISS Expedition 61 (NASA) ISS Expedition 61 was a mission to the International Space Station (ISS) conducted by NASA, the space agency of the United States, during October 2018 to April 2019. The crew on this expedition consisted of astronauts from various space agencies including NASA, Roscosmos (Russia), JAXA (Japan), ESA (Europe), and CSA (Canada). The primary focus of Expedition 61 was conducting scientific research, maintenance, and upgrades to the ISS. Significant experiments included studies on the effects of microgravity on plant growth, the investigation of combustion processes, and testing of advanced life support systems. This expedition also marked a significant milestone as it saw the departure of the SpaceX Dragon Cargo spacecraft, which delivered supplies to the ISS for NASA and returned with scientific samples. Overall, ISS Expedition 61 aimed at expanding human knowledge while paving the way for future manned space missions.